The Palazzo Poggi is a palace in Via Zamboni 33, Bologna, Italy. It is the headquarters of the University of Bologna and of the rector of the university.
The Palazzo Poggi was built as the home of Alessandro Poggi and his brother the future Cardinal Giovanni Poggio.
The building was erected between 1549 and 1560. The design of the Palazzo Poggi has been attributed to Bartolomeo Triachini. He was apparently given the commission for the Palazzo Poggi by the Bishop Giovanni Poggi shortly before he was elevated to Cardinal.
In 1714 the Palazzo Poggi became the House of the Instituto delle Scienze of Bologna. The Institute of Sciences was founded by Luigi Ferdinando Marsili. The Tower Observatory (La Specola) was built between 1712 and 1725. The library was built in 1744 following designs by Giuseppe Antonio Torri and Carlo Francesco Dotti.
The collection of images was begun in 1754. The monumental Great Hall of the institute was added to the north side of the palace in the eighteenth century, opened in 1756.